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Moduretic 5-50 y Diabetes

Resultado de la verificación de la interacción del medicamento Moduretic 5-50 y la enfermedad de Diabetes en la seguridad cuando se comparte.

Resultado de la verificación:

Moduretic 5-50 <> Diabetes

Relevancia: 23.07.2019 Examinador: P.M. Shkutko, M.D., in

Al verificar la interacción según fuentes acreditadas Drugs.com, Rxlist.com, Webmd.com, Medscape.com contraindicaciones o efectos secundarios se han encontrado que pueden causar daño o aumentar el efecto negativo cuando el medicamento se usa con esta enfermedad concomitante.

Consumidor:

Diuréticos ahorradores de potasio puede causar hiperpotasemia, lo cual puede resultar en peligro la vida arritmias cardíacas. Los pacientes con diabetes mellitus, con o sin nefropatía, pueden ser particularmente susceptibles a este tipo de efecto de estos fármacos debido a un defecto en el sistema renina-angiotensina-aldosterona eje. La terapia con diuréticos ahorradores de potasio se debe evitar, si es posible, en pacientes con diabetes, especialmente incontrolada o diabetes mellitus insulino-dependiente. Si estos medicamentos se utilizan, los niveles de potasio sérico y debe vigilarse la función renal a intervalos regulares. Determinación de electrolitos en suero es especialmente importante durante la iniciación de la terapia, después de un ajuste de la dosis y durante la enfermedad que puede alterar la función renal.

Fuentes

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"Product Information. Aldactone (spironolactone)." Searle, Skokie, IL.
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"Product Information. Midamor (amiloride)." Merck & Co, Inc, West Point, PA.
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Moduretic 5-50

Nombre genérico: amiloride / hydrochlorothiazide

Marca comerciale: Moduretic 5-50

Sinónimos: no

¿Qué es Moduretic 5-50?

Otro medicamento Eliminar

Moduretic 5-50 <> Diabetes

Relevancia: 23.07.2019 Examinador: P.M. Shkutko, M.D., in

Consumidor:

Los diuréticos tiazídicos pueden provocar hiperglucemia y glucosuria en pacientes con diabetes. También pueden precipitar la diabetes en pacientes prediabéticos. Estos efectos son generalmente reversibles después de la discontinuación de la droga. La terapia con diuréticos tiazídicos deben ser administrados con precaución en pacientes con diabetes mellitus, intolerancia a la glucosa, o una predisposición a la hiperglucemia. Los pacientes con diabetes mellitus deben ser monitoreados de cerca durante el tratamiento con tiazidas, y sus antidiabéticos régimen se ajusta en consecuencia.

Fuentes

Nielsen S, Schmitz A, Knudsen RE, Dollerup J, Mogensen CE "Enalapril versus bendroflumethiazide in type 2 diabetes complicated by hypertension." Q J Med 87 (1994): 747-54
Diamond MT "Hyperglycemic hyperosmolar coma associated with hydrochlorothiazide and pancreatitis." N Y State J Med 72 (1972): 1741-2
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Pickkers P, Schachter M, Hughes AD, Feher MD, Sever PS "Thiazide-induced hyperglycaemia: a role for calcium-activated potassium channels?" Diabetologia 39 (1996): 861-4
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"Product Information. Renese-R (reserpine-polythiazide)." Pfizer US Pharmaceuticals, New York, NY.
"Product Information. Thalitone (chlorthalidone)." Monarch Pharmaceuticals Inc, Bristol, TN.
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"Product Information. Enduron (methyclothiazide)." Abbott Pharmaceutical, Abbott Park, IL.
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"Product Information. Zaroxolyn (metolazone)." Rhone-Poulenc Rorer, Collegeville, PA.
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"Product Information. Metahydrin (trichlormethiazide)." Hoechst Marion-Roussel Inc, Kansas City, MO.
"Product Information. HydroDIURIL (hydrochlorothiazide)." Merck & Co, Inc, West Point, PA.
"Product Information. Diuril (chlorothiazide)." Merck & Co, Inc, West Point, PA.
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Elmfeldt D, Berglund G, Wedel H, Wilhelmsen L "Incidence and importance of metabolic side-effects during antihypertensive therapy." Acta Med Scand Suppl 672 (1983): 79-83
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"Product Information. Lozol (indapamide)." Rhone-Poulenc Rorer, Collegeville, PA.